Discovering The Developmental Origins of Obesity

The Polish Academy of Sciences in Olsztyn, Poland

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A restricted capacity of primary cultures of ear mesenchymal stem cells to differentiate to adipocytes

tn Toi and Ela POSTER edit lpk BGK May Toi revised May 06INTRODUCTION
One major goal of current research in brown adipose tissue (BAT) biology is to determine the molecular basis for its variable induction in white fat depots. The expression of BAT in white fat depends on developmental age, genotype and specific white fat depot. We have been testing the conditions for culturing the stromal vascular fraction (SVF) from inguinal fat (ingWAT), interscapular brown fat (iBAT) and ear mesenchymal stem cells (EMSC) to ascertain conditions for maximal expression of biomarkers for the brown and white differentiation programs.