Discovering The Developmental Origins of Obesity

The Polish Academy of Sciences in Olsztyn, Poland

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Heat from calcium cycling melts fat

Leslie P Kozak & Martin E Young

A new study in mice shows that sarcolipin, a small, regulatory protein of the intracellular calcium pump (SERCA) in skeletal muscle, is part of a nonshivering thermogenic mechanism for regulating both core body temperature and energy balance (pages 1575–1579).

Leslie P. Kozak is at the Institute of Animal Reproduction and Food Research of the Polish Academy of Science, Olsztyn, Poland.
Martin E. Young is in the Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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